Glucose Tolerance Test Results

Generex shares soar on preliminary clinical results of oral spray insulin

Generex has developed a proprietary platform technology for delivering drugs into the human body through the oral cavity (with no deposit in the lungs). Liquid formulations allow drugs in society usually administered by injection to be absorbed into the body through mucous membranes inside the mouth using our proprietary RapidMist ™ device.

Drug technology company Generex Biotechnology Corp. (OTC: GNBT) soared over 44% Friday after the company announced very encouraging preliminary results of two Phase 3 clinical trials testing the latest formulation of Generex Oral-lyn, conceived as an oral spray or a meal-time insulin for diabetics.

The first study, called the 084 trial, consisted of 463 patients with type 1 diabetes, while the second study used Prevoral 31 patients with obesity and glucose tolerance (IGT), a pre-diabetic syndrome type 2 . Type 1 diabetes are not currently treated with oral insulin, but with injections.

In diabetes, the pancreas can not produce insulin altogether, or production is insufficient for other reasons, leading to high levels of sugar in the blood, if left untreated. In a healthy person, insulin-secreting cells in the pancreas work quickly to stabilize blood sugar after a meal or drink is ingested.

The results of both trials showed that there was an increase in the flow of insulin in the blood during the first 30 minutes of administration, restoring a response to rapid-acting insulin after eating .The drug did not result in high levels of insulin two or three hours after use, reducing the potential for hypoglycemia, often seen in type 1 diabetes.

VP Generex 'Medical Officer, Dr. Gerald Bernstein, said: "These two studies confirm the value of Generex Oral-lyn in the two main types of diabetes."

"For people with type 1 there is a possibility to replace or supplement the bolus injections, with greater compliance to achieve their goals."

"For the millions of people with pre-diabetes, it provides an additional tool to control post-prandial (mealtime) glucose and delay the clinical onset of type 2 diabetes and reduce the risk of complications. All this will help mitigate the enormous economic burden of diabetes. "

In addition, Generex Oral-Lyn reduces blood gluc increase by a third party 2:15 to 3:00, demonstrating strong glycemic control, while showing a significant decrease in pre-diabetic in their hemoglobin A1c, a test that measures your average blood glucose over a period of three months.HbA1c levels were maintained at baseline values ​​of type 1 patients previously treated with injected insulin.

2 hour glucose tolerance test results & ??'s about IUI

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