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Government lists styrene as a carcinogen

Styrene, used in the building of fiberglass boats, is listed as “reasonably anticipated to be a human carcinogen based on limited evidence of carcinogenicity from studies in humans, sufficient evidence of carcinogenicity from studies in experimental animals and supporting data on mechanisms of carcinogenesis.”

A coalition of groups, including the National Marine Manufacturers Association , had fought against including styrene in the report, saying additional reviews were needed using a “rigorous unbiased transparent process.”

“We are disappointed that HHS has made this decision based solely on its own limited and misguided studies,” NMMA president Thom Dammrich said. “[The National Toxicology Program’s] deficient scientific process combined with their limited breadth of study in the face of a number of outside studies that were not evaluated demands that the listing be carefully examined.”

European Union regulators, a panel of internationally recognized epidemiologists and a Harvard Center for Risk Analysis study determined that styrene does not represent a human cancer concern, the Styrene Information and Research Center said in a recent letter to the department.

The listing is “based on a selective reading of the available scientific information that ignored a large number of important studies that did not support the [toxicology program’s] staff position. Not only was this information ignored, it was effectively excluded from the information presented to the NTP’s Board of Scientific Counselors [for review],” the letter stated.

Styrene is on the list based on human cancer studies, laboratory animal studies, and mechanistic scientific information, according to a statement from the department.

“The limited evidence of cancer from studies in humans shows lymphohematopoietic cancer and genetic damage in the white blood cells, or lymphocytes, of workers exposed to styrene,” according to the release. “The greatest exposure to styrene in the general population is through cigarette smoking. Workers in certain occupations may potentially be exposed to much higher levels of styrene than the general population.”

Of the other new substances on the report, the industrial chemical formaldehyde and a botanical known as aristolochic acids are listed as known human carcinogens. Six other substances — captafol, cobalt-tungsten carbide (in powder or hard metal form), certain inhalable glass wool fibers, o-nitrotoluene, riddelliine, and styrene — are added as substances that are reasonably anticipated to be human carcinogens.

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